Kleihauer-Betke (KB) Test. The KB test is performed to quantitate the number of fetal cells present in the maternal circulation. Once the size of the feto-maternal. Hemoglobin F quantitation by flow cytometry has been found to be simple, reliable, and more precise than the Kleihauer-Betke test,87 In the CAP. The Kleihauer-Betke test is a somewhat crude laboratory method used to screen maternal blood samples for the presence of fetal red blood cells.

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Apt—Downey test Kleihauer—Betke test. No items in your cart. In general this is not a problem. Improvement of the Kleihauer-Betke test by automated detection of fetal erythrocytes in maternal blood. Guidelines for the Management of a Pregnant Trauma Patient.

This page was last edited on 21 Augustat So, unless all stillbirths are tested, a large proportion of FMH will remain undetected.

Fetal movement counting Contraction rest test Nonstress test Vibroacoustic stimulation Biophysical profile Amniotic fluid index Umbilical Artery Dopplers. Myeloid blood tests CPT — The volume of fetal bleed is then calculated to determine how much additional RhIG is required.

No historical or clinical features reliably identify those in whom it may be the cause tesg an intrauterine death. This article needs additional citations for verification.


J Obstet Gynaecol Can. This disruption in the placental barrier may occur for many reasons, including intra-uterine fetal demise and trauma.

The red arrows indicate maternal cells, which appear as ghost cells. With a kleihsuer KB test, posttrauma electronic fetal monitoring duration may be limited safely. Prothrombin time Partial thromboplastin time Thrombin time Activated clotting time. Finally, anything which causes persistence of fetal hemoglobin in maternal blood cells will make interpretation much trickier.


Kleihauer-betke testing is important in all cases of maternal trauma.

In 71 cases, transplacental hemorrhage was assessed by maternal KB test. Intuitively, however, the risk of FMH would increase with higher magnitude blunt force, anterior placental location, and coagulopathies among other kleihaker. Show details Treasure Island FL: Cardiotocography Fetoscopy Fetal scalp blood testing Fetal scalp stimulation test. Blood drawing can be done klehiauer or postpartum at the convenience of the care provider and the mother; only if cesarean section is anticipated is it important to draw the sample prior to delivery.

Am J Public Health. Prevention of Rh alloimmunization. However, there are times when the additional dose is necessary due to massive red blood cell FMH and subsequent maternal immune response. It is important to note, however, that such a diagnosis is still not completely conclusive; fetuses losing large quantities of blood over long periods of time are able to compensate for this slower betks loss; since the KB stain tells us nothing with regard to the level of acuity of FMH.

Reticulocyte index Haptoglobin Mentzer index. Despite its widespread use, the KB test has significant limitations, including Low sensitivity Poor reproducibility. Nitro blue tetrazolium chloride test Complete blood count Absolute neutrophil count.

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McRoberts maneuver Woods’ screw maneuver Zavanelli maneuver. Kleihauer Betke test is utilized to determine if there is fetal blood in maternal circulation, with a threshold of 5 mL. A standard blood smear is prepared from the mother’s blood and exposed to an acid bath.

None of the trauma scoring systems betkr PTL. Articles needing additional references from November All articles needing additional references. Kleihauer test, showing fetal red blood cells in betek color, while adult red blood gest are only seen as “ghosts”.

The indicator cells will be at the center of the rosette, while the fetal RBCs will be clustered around the edges, like petals on a flower. Tdst comparative counts allow an estimate of whether a significant fetal-maternal transfusion occurred. Similar articles in PubMed. In the case of massive trauma, the KB test may be utilized primarily, without the preliminary use of the screening Rosette test. American Journal of Hematology. KB testing has obstetrical implications in diagnosis and prognosis of preterm labor, fetal demise, and other conditions.


Stillbirth assessment should, in all instances, incorporate testing of maternal blood for evidence of massive fetal-maternal hemorrhage. Reasoning that the magnitude of TPH would reflect uterine injury, we evaluated Kleihauer-Betke testing as an independent predictor of preterm labor PTL after maternal trauma. It takes advantage of the differential resistance of fetal hemoglobin to acid.

RBC count Hematocrit Hemoglobin. Potential Diagnosis The Rosette test is a qualitative screening test performed on a maternal blood sample to determine if FMH has occurred between a Rh-positive fetus and a Rh-negative mother and serves as a useful screening test. Fetal tissue Chorionic villus sampling Amniocentesis Blood Triple test Quad test Percutaneous umbilical cord blood sampling Apt test Kleihauer—Betke test Lung maturity Lecithin—sphingomyelin ratio Lamellar body count Fetal fibronectin test.

PMC ] [ PubMed: It was further determined that, when immersed in a citrate buffer pH of 3. KB testing has important advantages to all maternal trauma victims, regardless of Rh status. Fetal surgery Fetendo Podalic version External cephalic version Amnioinfusion. It has been shown that a positive KB test accurately predicts the risk of preterm labor following trauma, whereas clinical assessment does not Ref: